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Article

Structural coupling of 11-cis-7-methyl-retinal and amino acids at the ligand binding pocket of rhodopsin.

Photochemistry and photobiology - 1 Jan 2000

Aguilà Mònica, Toledo Darwin, Morillo Margarita, Dominguez Marta, Vaz Belén, Alvarez Rosana, de Lera Angel R, Garriga Pere

Abstract excerpt

It was previously shown that opsin can be regenerated with the newly synthesized 11-cis-7-methyl-retinal forming an artificial visual pigment. We now extend this study to include mutants at positions close to the retinal to further dissect the interactions of native and artificial chromophores with opsin. Several mutants at M207, W265 and Y268 have been obtained and regenerated with 11-cis-retinal and the...

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Identifiers

PMID: 19267873
DOI: 10.1111/j.1751-1097.2009.00535.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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