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Article

Phenotype-genotype correlation: challenge of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses.

Head & neck - 1 Oct 2006

Frattini Milo, Perrone Federica, Suardi Simona, Balestra Debora, Caramuta Stefano, Colombo Federica, Licitra Lisa, Cantù Giulio, Pierotti Marco A, Pilotti Silvana

Abstract excerpt

BACKGROUND: Intestinal-type adenocarcinoma (ITAC) of the nasal cavity and paranasal sinuses shows microscopic features indistinguishable from colorectal cancer. Our aim was to verify whether the morphologic resemblances mirror genetic profile similarities. METHODS: Twenty consecutive surgically treated ITAC cases, previously investigated for p16(INK4a) and TP53, were investigated for hMLH1, hMSH2, and...

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Source

Identifiers

PMID: 16906516
DOI: 10.1002/hed.20433

Genes

APC
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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