Article
FNDC3A is required for adhesion between spermatids and Sertoli cells.
Developmental biology - 15 Oct 2006
Obholz Kevin L, Akopyan Arsen, Waymire Katrina G, MacGregor Grant R
Abstract excerpt
Symplastic spermatids (sys) male mice are sterile due to a recessive mutation that causes defective adhesion between spermatids and Sertoli cells within the seminiferous epithelium. We show that the mutation in sys mice involves a deletion of 1.24 Mb of chromosome 14. Comparative genomic analysis suggests that this region contains only one gene, Fndc3a. A genetic complementation analysis using mice with a...
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