Article
Dissociable effects of dopamine and serotonin on reversal learning.
Neuron - 20 Nov 2013
den Ouden Hanneke E M, Daw Nathaniel D, Fernandez Guillén, Elshout Joris A, Rijpkema Mark, Hoogman Martine, Franke Barbara, Cools Roshan
Abstract excerpt
Serotonin and dopamine are speculated to subserve motivationally opponent functions, but this hypothesis has not been directly tested. We studied the role of these neurotransmitters in probabilistic reversal learning in nearly 700 individuals as a function of two polymorphisms in the genes encodi...
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