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Article

Risk-seeking for losses is associated with 5-HTTLPR, but not with transient changes in 5-HT levels.

Psychopharmacology - 1 Jul 2018

Neukam Philipp T, Kroemer Nils B, Deza Araujo Yacila I, Hellrung Lydia, Pooseh Shakoor, Rietschel Marcella, Witt Stephanie H, Schwarzenbolz Uwe, Henle Thomas, Smolka Michael N

Abstract excerpt

RATIONALE: Serotonin (5-HT) plays a key role in different aspects of value-based decision-making. A recent framework proposed that tonic 5-HT (together with dopamine, DA) codes future average reward expectations, providing a baseline against which possible choice outcomes are compared to guide decision-making. OBJECTIVES: To test whether high 5-HT levels decrease loss aversion, risk-seeking for gains, and...

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Identifiers

PMID: 29730700
DOI: 10.1007/s00213-018-4913-9

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MGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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