Article
Crystal structure and DNA-binding mode of Klebsiella pneumoniae primosomal PriB protein.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2012
Huang Yen-Hua, Lo Yu-Hua, Huang Wenya, Huang Cheng-Yang
Abstract excerpt
PriB is a primosomal DNA replication protein required for the re-initiation of replication in bacteria. In this study, we investigated the gene expression of PriB in Klebsiella pneumoniae (KpPriB) and characterized the gene product through crystal structural and functional analyses. Quantitative polymerase chain reaction analysis (Q-PCR) indicated that the 104-aa priB was expressed in K. pneumoniae with a C(T)...
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