Article
Role of chromosome stability and telomere length in the production of viable cell lines for somatic cell nuclear transfer
9 Aug 2006
Abstract excerpt
BACKGROUND: Somatic cell nuclear transfer (SCNT) provides an appealing alternative for the preservation of genetic material in non-domestic and endangered species. An important prerequisite for successful SCNT is the availability of good quality donor cells, as normal embryo development is dependent upon proper reprogramming of the donor genome so that embryonic genes can be appropriately expressed. The...
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