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Article

Robust measurement of telomere length in single cells

9 May 2013

Abstract excerpt

Measurement of telomere length currently requires a large population of cells, which masks telomere length heterogeneity in single cells, or requires FISH in metaphase arrested cells, posing technical challenges. A practical method for measuring telomere length in single cells has been lacking. We established a simple and robust approach for single-cell telomere length measurement (SCT-pqPCR). We first optimized...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 23661059
DOI: 10.1073/pnas.1306639110

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