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Long-Term Cryopreservation May Cause Genomic Instability and the Premature Senescence of Cells

25 Jan 2024

Abstract excerpt

Cryopreservation is an essential step for utilizing various cell types for biological research and medical purposes. At the same time, there is a lack of data on the effect of cryopreservation, especially when prolonged, on the karyotype of cells. In the present work, we analyzed the genetic stability of cells subjected to a cryopreservation procedure. The objects were immortalized Chinese hamster lung...

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PMID: 38338745
DOI: 10.3390/ijms25031467

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