Article
Key issues relating to the genetic stability and preservation of cells and cell banks.
Journal of parenteral science and technology : a publication of the Parenteral Drug Association - 1 Jan 2000
Simione F P
Abstract excerpt
The long term maintenance of genetically stable cells is important for ensuring reproducible results and continuity in the advance of microbiology, cell biology and biotechnology. As actively growing cultures, cells are constantly at risk of changing, and the necessity for subculturing living materials increases the chances for genetic change and contamination. Many techniques are available for stabilizing living...
Topics
- Bacteria
- Cell Survival
- Freeze Drying
- Genotype
- Quality Control
- Reproducibility of Results
- Tissue Banks
- Tissue Preservation