Article
No evidence for parental imprinting of mouse 22q11 gene orthologs.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2006
Maynard Thomas M, Meechan Daniel W, Heindel Clifford C, Peters Amanda Z, Hamer Robert M, Lieberman Jeffrey A, LaMantia Anthony-Samuel
Abstract excerpt
Non-Mendelian factors may influence central nervous system (CNS) phenotypes in patients with 22q11 Deletion Syndrome (22q11DS, also known as DiGeorge or Velocardiofacial Syndrome), and similar mechanisms may operate in mice carrying a deletion of one or more 22q11 gene orthologs. Accordingly, we examined the influence of parent of origin on expression of 25 murine 22q11 orthologs in the developing and mature CNS...
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