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Article

Sex-specific parent-of-origin allelic expression in the mouse brain.

Science (New York, N.Y.) - 6 Aug 2010

Gregg Christopher, Zhang Jiangwen, Butler James E, Haig David, Dulac Catherine

Abstract excerpt

Genomic imprinting results in preferential gene expression from paternally versus maternally inherited chromosomes. We used a genome-wide approach to uncover sex-specific parent-of-origin allelic effects in the adult mouse brain. Our study identified preferential selection of the maternally inherited X chromosome in glutamatergic neurons of the female cortex. Moreover, analysis of the cortex and hypothalamus...

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Identifiers

PMID: 20616234
DOI: 10.1126/science.1190831
PMCID: PMC2997643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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