Article
MDM2 SNP309 and SNP354 are not associated with lung cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2006
Pine Sharon R, Mechanic Leah E, Bowman Elise D, Welsh Judith A, Chanock Stephen C, Shields Peter G, Harris Curtis C
Abstract excerpt
A single nucleotide polymorphism (SNP) in the MDM2 promoter (a T to G exchange at nucleotide 309) has been found to be associated with tumor formation. Publication of this null report is important because an association between MDM2 SNP309 and lung cancer was previously reported in two independent studies. Our findings suggest that MDM2 SNP309 is not a strong factor in lung carcinogenesis. In addition, this is...
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