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Article

MDM2 309T>G polymorphism and risk of lung cancer in a Korean population.

Lung cancer (Amsterdam, Netherlands) - 1 Oct 2006

Park Sun Ha, Choi Jin Eun, Kim Eun Jin, Jang Jin Sung, Han Hyung Soo, Lee Won Kee, Kang Young Mo, Park Jae Yong

Abstract excerpt

BACKGROUND: The MDM2 protein plays an important role in regulating cell proliferation and apoptosis by interaction with multiple proteins including p53 and Rb. A polymorphism (309T>G) in the MDM2 promoter has been shown to result in higher levels of MDM2 RNA and protein. In order to evaluate the association of the MDM2 309T>G polymorphism and lung cancer risk, we carried out a case-control study in a Korean...

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Identifiers

PMID: 16876289
DOI: 10.1016/j.lungcan.2006.06.008

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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