Article
Interference of the induction of suppressor cells by a streptococcal preparation, OK-432 through the blocking of suppressor inducer T-cells.
International journal of immunopharmacology - 1 Jan 1990
Toge T, Kuroi K, Baba N, Kegoya Y, Takayama T, Yanagawa E
Abstract excerpt
The effect of OK-432 on suppressor inducer T cells in the generation of suppressor cells was investigated to determine its mechanism of action as an immunopotentiating agent. Suppressor cell activities induced by sera from patients with advanced cancer (stage III, IV or recurrence) were found to be as high as those induced by Con-A. Suppressor activity induced by Con-A or serum from cancer patients resided in...
Topics
- Antibodies, Monoclonal
- Biological Products
- Complement System Proteins
- Concanavalin A
- Flow Cytometry
- Humans
- In Vitro Techniques
- Lymphocyte Activation
- Phenotype
- Picibanil
- Staining and Labeling