Immunosuppressive activity of staphylococcal enterotoxin B. II. Activation of suppressor-effector cells by a staphylococcal enterotoxin B-induced suppressor factor.

Abstract excerpt

The capacity of staphylococcal enterotoxins to stimulate all T cells bearing certain T cell receptors has recently generated a great deal of interest. These toxins are believed to bind directly both to the TCR:CD4 complex via its V beta domains and to class II MHC molecules on accessory cells prior to T cell activation. Previous studies from this laboratory have demonstrated that staphylococcal enterotoxin B...

Topics

• Animals
• Antibodies, Monoclonal
• Antibody Formation
• Antigens, Surface
• Enterotoxins
• Histocompatibility Antigens Class II
• In Vitro Techniques
• Isoantibodies
• Lymphocyte Depletion
• Male
• Mice