Article
Suppression of the serT42 mutation with modified tRNA(1Ser) and tRNA(5Ser) genes.
Nucleic acids research - 11 Aug 1994
Yamada Y, Ishikura H
Abstract excerpt
Serine tRNA gene derivatives with altered anticodons were introduced to the temperature-sensitive serT42 mutant, whose tRNA(1Ser) shows a base substitution of A10 for wild type G10. When a low copy number vector-system was used, the growth and beta-galactosidase synthetic activity of the serT42 mutant were restored by complementation with the tRNA(5Ser) (T34) gene or the tRNA(1Ser) (G34) gene as well as the...
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