Article
Conservation in evolution for a small monomeric phenylalanyl-tRNA synthetase of the tRNA(Phe) recognition nucleotides and initial aminoacylation site.
Biochemistry - 9 Jan 1996
Aphasizhev R, Senger B, Rengers J U, Sprinzl M, Walter P, Nussbaum G, Fasiolo F
Abstract excerpt
We previously showed that yeast mitochondrial phenylalanyl-tRNA synthetase (MSF protein) is evolutionarily distant to the cytoplasmic counterpart based on a high degree of divergence in protein sequence, molecular mass, and quaternary structure. Using yeast cytoplasmic tRNA(Phe) which is efficiently aminoacylated by MSF protein, we report here the tRNA(Phe) primary site of aminoacylation and the identity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.