Article
Misexpression of the eyes absent family triggers the apoptotic program.
The Journal of biological chemistry - 1 Feb 2002
Clark S Wesley, Fee Brian E, Cleveland John L
Abstract excerpt
Genetic studies in Drosophila and mice have shown that eyes absent (eya) is an important and conserved transcriptional regulator of development. Along with eyeless/Pax6, sine oculis, and dachshund, eya genes function as master regulators in eye development and can induce ectopic eye formation. Furthermore, the loss-of-function mutants of these genes in the fly causes partial or complete loss of the compound eye,...
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