Article
Quantitative assessment of promoter methylation profiles in thyroid neoplasms.
The Journal of clinical endocrinology and metabolism - 1 Jul 2005
Hoque M O, Rosenbaum E, Westra W H, Xing M, Ladenson P, Zeiger M A, Sidransky D, Umbricht C B
Abstract excerpt
CONTEXT: Cancer-specific molecular markers are needed to supplement the cytopathological assessment of thyroid tumors, because a majority of patients with cytologically indeterminate nodules currently undergo thyroidectomy without a definitive diagnosis. OBJECTIVE: The aim of this study was the quantitative assessment of promoter hypermethylation and its relation to the BRAF mutation in thyroid tumors. DESIGN:...
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