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Article

Glucose activation of the glucagon receptor gene: functional dissimilarity with several other glucose response elements.

Annals of the New York Academy of Sciences - 1 Jul 2006

Portois Laurence, Virreira Myrna, Tastenoy Michèle, Svoboda Michal

Abstract excerpt

The glucagon receptor (GLR) expression is positively regulated by glucose. This regulation is allowed by the presence, in the promotor of the rat GLR gene, of a sequence feature similar to the two E-boxes motifs constituting the carbohydrate response elements (ChoRE) described for several glycolytic and lipogenic enzyme genes. Using reporter gene assays, we demonstrated here that, despite structural homologies...

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PMID: 16888215
DOI: 10.1196/annals.1317.068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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