Article
The CR2 receptor (CD21) shows increased expression in the more differentiated cells of an antigen-specific B cell line.
Cellular immunology - 1 Feb 1990
Pillemer S R, Tsokos G C, Barbieri S A, Balow J E, Golding B
Abstract excerpt
The complement receptor 2 (CR2; CD21), a 145,000 MW glycoprotein, has been useful as a marker of B lymphocyte maturation. It is expressed on the 1:13 monoclonal, EBV-transformed, B cell line which produces TNP-specific IgM-kappa and displays an in vitro capacity for differentiation. The line expresses the CD20+CD21+ phenotype. We studied whether CR2 receptor surface expression varied in relation to the cell cycle...
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