Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accumulation of Antigen-Driven Lymphoproliferations in Complement Receptor 2/CD21-/low B Cells From Patients With Sjögren's Syndrome.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Feb 2018

Glauzy Salomé, Boccitto Marco, Bannock Jason M, Delmotte Fabien R, Saadoun David, Cacoub Patrice, Ice John A, Sivils Kathy L, James Judith A, Wolin Sandra L, Meffre Eric

Abstract excerpt

OBJECTIVE: Patients with Sjögren's syndrome (SS) are prone to develop malignant lymphomas, and a correlation has been established between the lymphoproliferations occurring in these disorders and the presence in patients' blood of an unusual B cell population that down-regulates complement receptor 2/CD21. This study was undertaken to identify the B cell compartment from which these lymphoproliferations emerge...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique, Indirect

Share to Immunoprecipitation

Share to Lymphoproliferative Disorders

Share to Receptors, Antigen, B-Cell

Share to Receptors, Complement 3d

Share to Sjogren's Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 29073352
DOI: 10.1002/art.40352
PMCID: PMC5788702

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accumulation of Antigen-Driven Lymphoproliferations in Complement Receptor 2/CD21-/low B Cells From Patients With Sjögren's Syndrome.PMID 29073352Read ↗

Brief Report: Defective Early B Cell Tolerance Checkpoints in Sjögren's Syndrome PatientsSemantic proximity Read ↗

Evidence of B Cell Clonality and Investigation Into Properties of the IgM in Patients With Schnitzler Syndrome.Semantic proximity Read ↗

A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL.Semantic proximity Read ↗

T and B cell clonal expansion in Ras-associated lymphoproliferative disease (RALD) as revealed by next-generation sequencing.Semantic proximity Read ↗

Phenotypic perturbation of B cells in the Wiskott–Aldrich syndromeSemantic proximity Read ↗

Primary Sjögren's Syndrome Is Characterized by Distinct Phenotypic and Transcriptional Profiles of IgD+ Unswitched Memory B CellsSemantic proximity Read ↗

BAFF-induced changes in B cell antigen receptor-containing lipid rafts in Sjögren's syndrome.Semantic proximity Read ↗

Extrasalivary lymphoma development in Sjögren's syndrome: Clonal evolution from parotid gland lymphoproliferation and role of local triggeringSemantic proximity Read ↗

Salivary Gland Mucosa-Associated Lymphoid Tissue-Type Lymphoma From Sjögren's Syndrome Patients in the Majority Express Rheumatoid Factors Affinity-Selected for IgG.Semantic proximity Read ↗

Oligoclonal B lymphocyte expansion in the synovium of a patient with Behçet's disease.Semantic proximity Read ↗

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivitySemantic proximity Read ↗

Characterization of prelymphomatous stages of B cell lymphoproliferation in Sjögren's syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.