Article
AI-3 synthesis is not dependent on luxS in Escherichia coli.
Journal of bacteriology - 1 Aug 2006
Walters Matthew, Sircili Marcelo P, Sperandio Vanessa
Abstract excerpt
The quorum-sensing (QS) signal autoinducer-2 (AI-2) has been proposed to promote interspecies signaling in a broad range of bacterial species. AI-2 is spontaneously derived from 4,5-dihydroxy-2,3-pentanedione that, along with homocysteine, is produced by cleavage of S-adenosylhomocysteine (SAH) and S-ribosylhomocysteine by the Pfs and LuxS enzymes. Numerous phenotypes have been attributed to AI-2 QS signaling...
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