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Article

Transcriptional and metabolomic consequences of LuxS inactivation reveal a metabolic rather than quorum-sensing role for LuxS in Lactobacillus reuteri 100-23.

Journal of bacteriology - 1 Apr 2012

Wilson Charlotte M, Aggio Raphael B M, O'Toole Paul W, Villas-Boas Silas, Tannock Gerald W

Abstract excerpt

Autoinducer-2 (AI-2)-mediated quorum sensing has been extensively studied in relation to the regulation of microbial behavior. There are, however, two potential roles for the AI-2 synthase (LuxS). The first is in the production of AI-2 and the second is as an enzyme in the activated methyl cycle,...

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Identifiers

PMID: 22287522
DOI: 10.1128/JB.06318-11
PMCID: PMC3302454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22287522-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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