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Article

Growth deficiencies of Neisseria meningitidis pfs and luxS mutants are not due to inactivation of quorum sensing.

Journal of bacteriology - 1 Feb 2009

Heurlier Karin, Vendeville Agnès, Halliday Nigel, Green Andrew, Winzer Klaus, Tang Christoph M, Hardie Kim R

Abstract excerpt

The activated methyl cycle (AMC) is a central metabolic pathway used to generate (and recycle) several important metabolites and enable methylation. Pfs and LuxS are considered integral components of this pathway because they convert S-adenosylhomocysteine (SAH) to S-ribosylhomocysteine (SRH) and S-ribosylhomocysteine to homocysteine (HCY), respectively. The latter reaction has a second function since it also...

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Identifiers

PMID: 19074394
DOI: 10.1128/JB.01170-08
PMCID: PMC2632006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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