Article
Deletion mutations caused by DNA strand slippage in Acinetobacter baylyi.
Applied and environmental microbiology - 1 Aug 2006
Gore Jeremy M, Ran F Ann, Ornston L Nicholas
Abstract excerpt
Short nucleotide sequence repetitions in DNA can provide selective benefits and also can be a source of genetic instability arising from deletions guided by pairing between misaligned strands. These findings raise the question of how the frequency of deletion mutations is influenced by the length of sequence repetitions and by the distance between them. An experimental approach to this question was presented by...
Topics
- Acinetobacter
- Base Sequence
- Culture Media
- DNA, Bacterial
- DNA, Single-Stranded
- Escherichia coli
- Mutation
- Plasmids
- Protocatechuate-3,4-Dioxygenase
- Repetitive Sequences, Nucleic Acid
- Reproducibility of Results