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Article

Genome instability mediates the loss of key traits by Acinetobacter baylyi ADP1 during laboratory evolution.

Journal of bacteriology - 1 Mar 2015

Renda Brian A, Dasgupta Aurko, Leon Dacia, Barrick Jeffrey E

Abstract excerpt

Acinetobacter baylyi ADP1 has the potential to be a versatile bacterial host for synthetic biology because it is naturally transformable. To examine the genetic reliability of this desirable trait and to understand the potential stability of other engineered capabilities, we propagated ADP1 for 1,000 generations of growth in rich nutrient broth and analyzed the genetic changes that evolved by whole-genome...

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Identifiers

PMID: 25512307
DOI: 10.1128/JB.02263-14
PMCID: PMC4325111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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