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Article

The role of the Met98Lys optineurin variant in inherited optic nerve diseases.

The British journal of ophthalmology - 1 Nov 2006

Craig J E, Hewitt A W, Dimasi D P, Howell N, Toomes C, Cohn A C, Mackey D A

Abstract excerpt

AIMS: To investigate the role of the common OPTN Met98Lys variant as a risk allele in open-angle glaucoma (OAG), autosomal dominant optic atrophy (ADOA) and Leber's hereditary optic neuropathy (LHON). METHODS: The presence of the Met98Lys variant was determined in a total of 498 (128 with normal-tension glaucoma (NTG)) patients with OAG, 29 patients who had myocilin-related OAG, 101 patients from ADOA pedigrees,...

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Source

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Identifiers

PMID: 16885188
DOI: 10.1136/bjo.2006.099333
PMCID: PMC1857489

Genes

OPTN
MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of the Met98Lys optineurin variant in inherited optic nerve diseases.PMID 16885188Read ↗

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