Article
Lack of association of mutations in optineurin with disease in patients with adult-onset primary open-angle glaucoma.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Aug 2003
Wiggs Janey L, Auguste Josette, Allingham R Rand, Flor Jason D, Pericak-Vance Margaret A, Rogers Kathryn, LaRocque Karen R, Graham Felicia L, Broomer Bob, Del Bono Elizabeth, Haines Jonathan L, Hauser Michael
Abstract excerpt
OBJECTIVE: To determine whether mutations in the optineurin gene contribute to susceptibility to adult-onset primary open-angle glaucoma. METHODS: The optineurin gene was screened in 86 probands with adult-onset primary open-angle glaucoma and in 80 age-matched control subjects. Exons 4 and 5, co...
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