Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in optineurin (OPTN) allele frequencies between and within populations.

Molecular vision - 2 Feb 2007

Ayala-Lugo Rosa M, Pawar Hemant, Reed David M, Lichter Paul R, Moroi Sayoko E, Page Michael, Eadie James, Azocar Veronica, Maul Eugenio, Ntim-Amponsah Christine, Bromley William, Obeng-Nyarkoh Ebenezer, Johnson A Tim, Kijek Theresa Guckian, Downs Catherine A, Johnson Jenae M, Perez-Grossmann Rodolfo A, Guevara-Fujita Maria-Luisa, Fujita Ricardo, Wallace Margaret R, Richards Julia E

Abstract excerpt

PURPOSE: To evaluate the extent to which mutations in the optineurin (OPTN) glaucoma gene play a role in glaucoma in different populations. METHODS: Case-controlled study of OPTN sequence variants in individuals with or without glaucoma in populations of different ancestral origins and evaluate previous OPTN reports. We analyzed 314 subjects with African, Asian, Caucasian and Hispanic ancestries included 229...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glaucoma
Share to Glaucoma, Open-Angle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutamine

Share to Hispanic or Latino

Share to Intraocular Pressure

Share to Methionine

Share to Racial Groups

Share to Transcription Factor TFIIIA

Source

Open in PubMed Open full text

Identifiers

PMID: 17293779
PMCID: PMC2533035

Genes

OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in optineurin (OPTN) allele frequencies between and within populations.PMID 17293779Read ↗

Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: the Blue Mountains Eye Study.Semantic proximity Read ↗

Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States.Semantic proximity Read ↗

Analysis of rare variants and common haplotypes in the optineurin gene in Swedish glaucoma cases.Semantic proximity Read ↗

Lack of association between optineurin gene variants T34T, E50K, M98K, 691_692insAG and R545Q and primary open angle glaucoma in Brazilian patients.Semantic proximity Read ↗

OPTN gene: profile of patients with glaucoma from India.Semantic proximity Read ↗

Optineurin coding variants in Ghanaian patients with primary open-angle glaucoma.Semantic proximity Read ↗

Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population.Semantic proximity Read ↗

Mutations in the optineurin gene in Japanese patients with primary open-angle glaucoma and normal tension glaucoma.Semantic proximity Read ↗

Different optineurin mutation pattern in primary open-angle glaucoma.Semantic proximity Read ↗

Prevalence of optineurin sequence variants in adult primary open angle glaucoma: implications for diagnostic testing.Semantic proximity Read ↗

Meta-analysis of association between optineurin gene and primary open-angle glaucoma.Semantic proximity Read ↗

Association study of optineurin gene polymorphisms T34T and M98K with normal tension glaucoma in a Turkish cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.