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Article

Prevalence of myocilin and optineurin sequence variants in German normal tension glaucoma patients.

Molecular vision - 18 Apr 2005

Weisschuh Nicole, Neumann Dorit, Wolf Christiane, Wissinger Bernd, Gramer Eugen

Abstract excerpt

PURPOSE: To determine the prevalence of optineurin (OPTN) and myocilin (MYOC) sequence variants in a cohort of German patients with normal tension glaucoma. METHODS: All coding exons of the OPTN and MYOC genes were amplified by PCR from genomic DNA and subjected to direct DNA sequencing. Analysis of sequence variants in controls was done by denaturing high performance liquid chromatography (DHPLC) and restriction...

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Source

Identifiers

PMID: 15851979

Genes

OPTN
MYOC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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