Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ribosomal DNA transcription-dependent processes interfere with chromosome segregation.

Molecular and cellular biology - 1 Aug 2006

Tomson Brett N, D'Amours Damien, Adamson Brittany S, Aragon Luis, Amon Angelika

Abstract excerpt

The ribosomal DNA (rDNA) is a specialized genomic region not only owing to its function as the nucleolar organizing region (NOR) but also because it is repetitive in nature and, at least in budding yeast, silenced for polymerase II (Pol II)-mediated transcription. Furthermore, cohesin-independent linkages hold the sister chromatids together at the rDNA loci, and their resolution requires the activity of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to Chromosomes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Ribosomal

Share to Protein Tyrosine Phosphatases

Share to Pyrrolidinones

Share to Repetitive Sequences, Nucleic Acid

Share to RNA Polymerase I

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 16880532
DOI: 10.1128/MCB.00693-06
PMCID: PMC1592809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ribosomal DNA transcription-dependent processes interfere with chromosome segregation.PMID 16880532Read ↗

Transcription of ribosomal genes can cause nondisjunction.Semantic proximity Read ↗

Nucleolar segregation lags behind the rest of the genome and requires Cdc14p activation by the FEAR network.Semantic proximity Read ↗

Cohesion promotes nucleolar structure and function.Semantic proximity Read ↗

Cdc14 and condensin control the dissolution of cohesin-independent chromosome linkages at repeated DNA.Semantic proximity Read ↗

Involvement of condensin-directed gene associations in the organization and regulation of chromosome territories during the cell cycle.Semantic proximity Read ↗

Cyclin-specific control of ribosomal DNA segregation.Semantic proximity Read ↗

Spindle-independent condensation-mediated segregation of yeast ribosomal DNA in late anaphase.Semantic proximity Read ↗

The cohesin loader NIPBL interacts with pre-ribosomal RNA and treacle to regulate ribosomal RNA synthesisSemantic proximity Read ↗

Relocation of rDNA repeats for repair is dependent on SUMO-mediated nucleolar release by the Cdc48/p97 segregaseSemantic proximity Read ↗

Paf1 Counteracts transcriptional arrest to maintain rDNA stability during pol I elongation.Semantic proximity Read ↗

Smc5-Smc6 complex preserves nucleolar integrity in S. cerevisiae.Semantic proximity Read ↗

Nucleolar release of rDNA repeats for repair involves SUMO-mediated untethering by the Cdc48/p97 segregase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.