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Article

Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score

4 Jul 2006

Abstract excerpt

OBJECTIVE: To investigate the expression and potential clinical usefulness of structure-specific flap endonuclease 1 (FEN-1) in human primary prostate cancer using tissue microarray technology, as FEN-1 was recently identified to be overexpressed in CL1.1, the most aggressive clone generated from the hormone-refractory prostate cancer cell line CL1. MATERIALS AND METHODS: Immunohistochemistry was performed on...

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PMID: 16879693
DOI: 10.1111/j.1464-410x.2006.06224.x

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