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Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

26 Jul 2017

Abstract excerpt

BACKGROUND: Animal model experiments have suggested a role of the DNA repair protein ERCC1 (Excision Repair Cross-Complementation Group 1) in prostate cancer progression. METHODS: To better understand the impact of ERCC1 protein expression in human prostate cancer, a preexisting tissue microarray (TMA) containing more than 12,000 prostate cancer specimens was analyzed by immunohistochemistry and data were...

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PMID: 28747165
DOI: 10.1186/s12885-017-3489-9

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