Article
Interchromosomal interactions and olfactory receptor choice.
Cell - 28 Jul 2006
Lomvardas Stavros, Barnea Gilad, Pisapia David J, Mendelsohn Monica, Kirkland Jennifer, Axel Richard
Abstract excerpt
The expression of a single odorant receptor (OR) gene from a large gene family in individual sensory neurons is an essential feature of the organization and function of the olfactory system. We have used chromosome conformation capture to demonstrate the specific association of an enhancer element, H, on chromosome 14 with multiple OR gene promoters on different chromosomes. DNA and RNA fluorescence in situ...
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