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Article

Developing live<i>Shigella</i>vaccines using Î» Red recombineering

9 Jun 2006

Abstract excerpt

Live attenuated Shigella vaccines have shown promise in inducing protective immune responses in human clinical trials and as carriers of heterologous antigens from other mucosal pathogens. In the past, construction of Shigella vaccine strains relied on classical allelic exchange systems to genetically engineer the bacterial genome. These systems require extensive in vitro engineering of long homologous sequences...

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Identifiers

PMID: 16872384
DOI: 10.1111/j.1574-695x.2006.00118.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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