Article

High rates of genome rearrangements and pathogenicity of <i>Shigella</i> spp

2020-06-12

Abstract excerpt

Shigella are pathogens originating within the Escherichia lineage but frequently classified as a separate genus. Shigella genomes contain numerous insertion sequences (ISs) that lead to pseudogenization of affected genes and an increase of non-homologous recombination. Here, we study 414 genomes of E. coli and Shigella strains to assess the contribution of genomic rearrangements to Shigella evolution. We foun...

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Literature Corpus work: 8b55e43c-b2bd-50d1-83b2-c223e597075a
DOI: 10.1101/2020.06.12.147751

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