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Article

MYPT1 mutants demonstrate the importance of aa 888-928 for the interaction with PKGIalpha.

American journal of physiology. Cell physiology - 1 Jan 2007

Given Allison M, Ogut Ozgur, Brozovich Frank V

Abstract excerpt

During nitric oxide signaling, type Ialpha cGMP-dependent protein kinase (PKGIalpha) activates myosin light chain (MLC) phosphatase through an interaction with the 130-kDa myosin targeting subunit (MYPT1), leading to dephosphorylation of 20-kDa MLC and vasodilatation. It has been suggested that t...

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Source

Identifiers

PMID: 16870832
DOI: 10.1152/ajpcell.00175.2006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16870832-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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