Article
Typing of HLA-DQA1 and DQB1 using DNA single-strand conformation polymorphism.
Human immunology - 1 Mar 1992
Carrington M, Miller T, White M, Gerrard B, Stewart C, Dean M, Mann D
Abstract excerpt
The technique of single-strand conformation polymorphism (SSCP), which is capable of distinguishing DNA sequence variability, was adapted to the identification of the HLA-DQA1 and DQB1 alleles. Eight DQA1 alleles and 12 DQB1 alleles were distinguished by amplifying the second exon of the genes in...
Topics
- Alleles
- Base Sequence
- DNA, Single-Stranded
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Humans
- Molecular Sequence Data
- Nucleic Acid Conformation