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Article

Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues.

Expert opinion on drug metabolism & toxicology - 1 Jun 2006

Turman Cheri M, Hatley Jade M, Ryder Daniel J, Ravindranath Vijayalakshmi, Strobel Henry W

Abstract excerpt

The human cytochrome P450 (CYP) superfamily of enzymes regulate hepatic phase 1 drug metabolism and subsequently play a significant role in pharmacokinetics, drug discovery and drug development. Alternative splicing of the cytochrome CYP gene transcripts enhances gene diversity and may play a role in transcriptional regulation of certain CYP proteins. Tissue-specific alternative splicing of CYPs is significant...

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Source

Identifiers

PMID: 16863442
DOI: 10.1517/17425255.2.3.399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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