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Article

Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain.

Journal of neurochemistry - 1 May 2005

Chinta Shankar J, Kommaddi Reddy P, Turman Cheri M, Strobel Henry W, Ravindranath Vijayalakshmi

Abstract excerpt

Cytochrome P-450 function as mono-oxygenases and metabolize xenobiotics. CYP1A1, a cytochrome P-450 enzyme, bioactivates polycyclic aromatic hydrocarbons to reactive metabolite(s) that bind to DNA and initiate carcinogenesis. Northern and immunoblot analyses revealed constitutive expression of Cy...

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Source

Identifiers

PMID: 15836631
DOI: 10.1111/j.1471-4159.2005.03061.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15836631-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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