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Article

Double immunohistochemical detection of transmitter phenotype of proliferating cells using bromodeoxyuridine.

Neuroscience letters - 28 Oct 1991

Kono T, Takada M, Wu J Y, Kitai S T

Abstract excerpt

We describe a new method that can determine transmitter phenotype of proliferating nerve cells at a given age. The procedure is based on indirect sequential double antigen immunofluorescence histochemistry for transmitter-synthesizing enzymes (glutamic acid decarboxylase and tyrosine hydroxylase) and the thymidine analogue, bromodeoxyuridine. The method permits simple, rapid, and effective anatomical detection,...

Topics

Animals
Brain
Bromodeoxyuridine
Cell Division
Female
Fluorescent Antibody Technique
Gestational Age
Glutamate Decarboxylase
Immunohistochemistry
Neurotransmitter Agents
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy

Rats

Rats, Inbred Strains

Substantia Nigra

Tyrosine 3-Monooxygenase

Source

Identifiers

PMID: 1686305
DOI: 10.1016/0304-3940(91)90446-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1686305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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