Article
Effect of polymorphisms of the MTHFR and APOE genes on susceptibility to diabetes and severity of diabetic retinopathy in Brazilian patients.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 2006
Errera F I V, Silva M E R, Yeh E, Maranduba C M C, Folco B, Takahashi W, Pereira A C, Krieger J E, Passos-Bueno M R
Abstract excerpt
Diabetes mellitus (DM) is a highly prevalent complex genetic disorder. There has been a worldwide effort in the identification of susceptibility genes for DM and its complications, and the 5-10-methylenetetrahydrofolate reductase (MTHFR) and apolipoprotein-E (APOE) genes have been considered good candidate susceptibility genes to this condition. The objectives of the present study were to determine if the 677T...
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