Article
The epsilon4 allele of apolipoprotein E gene is a potential risk factor for the severity of macular edema in type 2 diabetic Mexican patients.
Ophthalmic genetics - 1 Mar 2002
Santos Arturo, Salguero Mario L, Gurrola Carmen, Muñoz Francisco, Roig-Melo Enrique, Panduro Arturo
Abstract excerpt
PURPOSE: The objective of this study was to determine the relationship between APOE polymorphism and the severity of retinal hard exudates in Mexican patients with type 2 diabetes. METHODS: We studied 36 patients with diabetic retinopathy and 22 unrelated and apparently healthy age-matched individuals. Blood samples for DNA genotyping and lipid profile were taken. Genotyping of polymorphic APOE alleles was done...
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