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Article

MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients.

Journal of diabetes and its complications - 1 Jan 2000

Maeda Makiko, Yamamoto Isamu, Fukuda Masakatsu, Motomura Takashi, Nishida Mari, Nonen Shinpei, Fujio Yasushi, Kasayama Soji, Azuma Junichi

Abstract excerpt

AIMS: Previously, we have proposed that methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (C677T) could be a risk factor for diabetic retinopathy. To support our suggestion, we examined in detail the association of MTHFR polymorphism with diabetic retinopathy and nephropathy in Japanese type 2 diabetic patients. METHODS: Subjects (n=190) were free of cardiovascular diseases and were not on...

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Source

Identifiers

PMID: 18280442
DOI: 10.1016/j.jdiacomp.2006.12.002

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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