Article
Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis.
Arthritis research & therapy - 1 Jan 2006
Mewar Devesh, Coote Annabel, Moore David J, Marinou Ioanna, Keyworth Jodie, Dickson Marion C, Montgomery Doug S, Binks Michael H, Wilson Anthony G
Abstract excerpt
Several recent publications have established a strong association between anti-cyclic citrullinated peptide antibody (anti-CCP)-positive rheumatoid arthritis (RA) and carriage of shared epitope (SE) alleles. Although anti-CCP have also been associated with more severe RA, the issue of whether this is independent of rheumatoid factor (RF) has not been addressed. To identify associations between RF, anti-CCP, SE...
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