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Article

Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark.

Arthritis and rheumatism - 1 May 2007

Pedersen Merete, Jacobsen Søren, Garred Peter, Madsen Hans O, Klarlund Mette, Svejgaard Arne, Pedersen Bo V, Wohlfahrt Jan, Frisch Morten

Abstract excerpt

OBJECTIVE: To study the role of shared epitope (SE) susceptibility genes, alone and in combination with tobacco smoking and other environmental risk factors, for risk of subtypes of rheumatoid arthritis (RA) defined by the presence or absence of serum antibodies against cyclic citrullinated peptides (CCPs). METHODS: To address these issues, a nationwide case-control study was conducted in Denmark during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17469102
DOI: 10.1002/art.22597

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Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark.PMID 17469102Read ↗

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