Article
HLA-DRB1alleles and osteoarthritis in a group of patients living in Liguria-Italy.
Minerva medica - 1 Jun 2006
Rovetta G, Buffrini L, Monteforte P, Grignolo M C, Molfetta L
Abstract excerpt
AIM: Osteoarthritis (OA), a degenerative arthro-pathy, produces damage and cartilage loss in one or more joints. Genetic factors contribute substantially to the risk of OA. The nature of the genetic influence in OA is speculative and may involve both a structural defect (i.e. collagen), alterations in cartilage or bone metabolism. Analyses of the frequencies of HLA antigens in various OA populations showed...
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