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Article

Association of HLA-DRB1*02 with osteoarthritis in a cohort of 106 patients.

Rheumatology (Oxford, England) - 1 Jun 2002

Moos V, Menard J, Sieper J, Sparmann M, Müller B

Abstract excerpt

OBJECTIVE: We have previously shown that the inflammatory cytokines tumour necrosis factor alpha (TNF-alpha) and interleukin (IL) 6 or IL-1beta are up-regulated in chondrocytes of patients with osteoarthritis (OA). However, the inflammatory responses associated with OA are of low grade and restricted. To investigate the involvement of the immune system in the pathogenesis of OA, we analysed patients for their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12048293
DOI: 10.1093/rheumatology/41.6.666

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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